| Total Population | 36130 | 2020 Decennial Census |
| Median Household Income | 52943 | 2024 American Community Survey 5-Year Estimates |
| Bachelor's Degree or Higher | 15.8 | 2024 American Community Survey 5-Year Estimates |
| Employment Rate | 42.6 | 2024 American Community Survey 5-Year Estimates |
| Total Housing Units | 16627 | 2024 American Community Survey 5-Year Estimates |
| Without Health Care Coverage | 6.5 | 2024 American Community Survey 5-Year Estimates |
| Total Employer Establishments | 607 | 2023 Economic Surveys Business Patterns |
| Total Households | 13905 | 2024 American Community Survey 5-Year Estimates |
| Hispanic or Latino (of any race) | 452 | 2020 Decennial Census |
| Areas Located Within | , |
| Unemployment Rate in Wise County, VA | 2026-06-01 |
| 90% Confidence Interval Upper Bound of Estimate of Percent of People of All Ages in Poverty for Wise County, VA | 2024-01-01 |
| Percent of Population Below the Poverty Level (5-year estimate) in Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Upper Bound of Estimate of Median Household Income for Wise County, VA | 2024-01-01 |
| Resident Population in Wise County, VA | 2025-01-01 |
| High School Graduate or Higher (5-year estimate) in Wise County, VA | 2024-01-01 |
| Age-Adjusted Premature Death Rate for Wise County, VA | 2020-01-01 |
| Burdened Households (5-year estimate) in Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Lower Bound of Estimate of Median Household Income for Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Upper Bound of Estimate of Percent of Related Children Age 5-17 in Families in Poverty for Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Upper Bound of Estimate of Percent of People Age 0-17 in Poverty for Wise County, VA | 2024-01-01 |
| Estimate of Median Household Income for Wise County, VA | 2024-01-01 |
| New Private Housing Structures Authorized by Building Permits for Wise County, VA | 2025-01-01 |
| Income Inequality in Wise County, VA | 2024-01-01 |
| Estimated Percent of People of All Ages in Poverty for Wise County, VA | 2024-01-01 |
| Population Estimate, Total, Not Hispanic or Latino, Two or More Races (5-year estimate) in Wise County, VA | 2024-01-01 |
| Estimate of People of All Ages in Poverty in Wise County, VA | 2024-01-01 |
| Poverty Universe, All Ages for Wise County, VA | 2024-01-01 |
| Combined Violent and Property Crime Offenses Known to Law Enforcement in Wise County, VA (DISCONTINUED) | 2021-01-01 |
| Bachelor's Degree or Higher (5-year estimate) in Wise County, VA | 2024-01-01 |
| Net County-to-County Migration Flow (5-year estimate) for Wise County, VA (DISCONTINUED) | 2020-01-01 |
| Estimate of People Age 0-17 in Poverty in Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Upper Bound of Estimate of Related Children Age 5-17 in Families in Poverty for Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Lower Bound of Estimate of Percent of People of All Ages in Poverty for Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Upper Bound of Estimate of People Age 0-17 in Poverty for Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Lower Bound of Estimate of Percent of Related Children Age 5-17 in Families in Poverty for Wise County, VA | 2024-01-01 |
| SNAP Benefits Recipients in Wise County, VA | 2023-01-01 |
| Premature Death Rate for Wise County, VA | 2020-01-01 |
| Homeownership Rate (5-year estimate) for Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Lower Bound of Estimate of Percent of People Age 0-17 in Poverty for Wise County, VA | 2024-01-01 |
| Population Estimate, Total, Not Hispanic or Latino, White Alone (5-year estimate) in Wise County, VA | 2024-01-01 |
| Population Estimate, Total, Not Hispanic or Latino, Black or African American Alone (5-year estimate) in Wise County, VA | 2024-01-01 |
| Mean Commuting Time for Workers (5-year estimate) in Wise County, VA | 2024-01-01 |
| 90% Confidence Interval Lower Bound of Estimate of People of All Ages in Poverty for Wise County, VA | 2024-01-01 |
| Population Estimate, Total, Hispanic or Latino, Black or African American Alone (5-year estimate) in Wise County, VA | 2024-01-01 |
| People 25 Years and Over Who Have Completed an Associate's Degree or Higher (5-year estimate) in Wise County, VA | 2024-01-01 |
| U.S. Granted Utility Patents Originating in Wise County, VA | 2015-01-01 |
| Rate of Preventable Hospital Admissions (5-year estimate) in Wise County, VA (DISCONTINUED) | 2015-01-01 |
| Estimated Percent of People Age 0-17 in Poverty for Wise County, VA | 2024-01-01 |
| Single-Parent Households with Children as a Percentage of Households with Children (5-year estimate) in Wise County, VA | 2024-01-01 |
| Quarterly Financial Report / November 29, 2022 |
| Quarterly Financial Report - Retail / November 29, 2022 |
| Advance Retail Inventories / November 29, 2022 |
| Advance Wholesale Inventories / November 29, 2022 |
| Housing Vacancies and Homeownership / November 29, 2022 |
| Monthly Wholesale Trade: Sales and Inventories / November 29, 2022 |
| Advanced Monthly Sales for Retail and Food Services / November 29, 2022 |
| Advance Monthly Manufacturers' Shipments, Inventories, and Orders / November 29, 2022 |
| New Home Sales / November 29, 2022 |
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| Quarterly Financial Report - Retail Trade / May 4, 2021 |
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| Quarterly Financial Report - Manufacturing, Mining, Wholesale Trade, and Selected Service Industries / May 4, 2021 |